- Original Article
- Serological investigation of Ureaplasma urealyticum in Korean preterm infants
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Ho Seon Eun, Soon Min Lee, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee
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Clin Exp Pediatr. 2013;56(11):477-481. Published online November 27, 2013
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Purpose Ureaplasma colonization is related with perinatal complications in preterm infants. Little is known about the difference in virulence among various Ureaplasma urealyticum serovars. The aim of this study was to determine U. urealyticum serovars of preterm infants in order to assess whether any of the serovars were associated with bronchopulmonary dysplasia (BPD). MethodsThree hundred forty-four preterm infants with a gestational age... |
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- Case Report
- Successful pleurodesis with OK-432 in preterm infants with persistent pleural effusion
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Jeong Eun Kim, Chul Lee, Kook In Park, Min Soo Park, Ran Namgung, In Kyu Park
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Clin Exp Pediatr. 2012;55(5):177-180. Published online May 21, 2012
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OK-432 (picibanil) is an inactivated preparation of Streptococcus pyogenes that causes pleurodesis by inducing a strong inflammatory response. Intrapleural instillation of OK-432 has recently been used to successfully treat neonatal and fetal chylothorax. Here we report a trial of intrapleural instillation of OK-432 in two preterm infants who were born with hydrops fetalis and massive bilateral pleural effusion. Both cases... |
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- Original Article
- Effect of severe neonatal morbidities on long term outcome in extremely low birthweight infants
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Kyo Yeon Koo, Jeong Eun Kim, Soon Min Lee, Ran Namgung, Min Soo Park, Kook In Park, Chul Lee
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Clin Exp Pediatr. 2010;53(6):694-700. Published online June 23, 2010
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Purpose To assess the validity of individual and combined prognostic effects of severe bronchopulmonary dysplasia (BPD), brain injury, retinopathy of prematurity (ROP), and parenteral nutrition associated cholestasis (PNAC). MethodsWe retrospectively analyzed the medical records of 80 extremely low birthweight (ELBW) infants admitted to the neonatal intensive care unit (NICU) of the Severance Children's Hospital, and who survived to a postmenstrual age of... |
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- Case Report
- A case of postoperative nasopharyngeal reflux associated with retropharyngeal lymphangioma in newborn infant
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Kyo Yeon Koo, Jun Seok Lee, Soon Min Lee, Min Soo Park, Ran Namgung, Kook In Park, Chul Lee, Choon Sik Yoon, Woo Hee Jung, Hong Shik Choi
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Clin Exp Pediatr. 2010;53(2):258-261. Published online February 15, 2010
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Lymphangioma is a rare benign congenital tumor of the lymphatic system, which is commonly diagnosed before 2 years of age. In the natronal report, cystic lymphangioma was usually reported as a huge translucent mass located in the head and neck area. It's occurrence in retropharyngeal space with respiratory obstruction and swallowing difficulty in neonate is extremely rare and postoperative nasopharyngeal... |
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- Original Article
- Survival analysis of spinal muscular atrophy type I
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Hyun Bin Park, Soon Min Lee, Jin Sung Lee, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee
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Clin Exp Pediatr. 2010;53(11):965-970. Published online November 30, 2010
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Purpose The life expectancy of patients with spinal muscular atrophy (SMA) type I is generally considered to be less than 2 years. Recently, with the introduction of proactive treatments, a longer survival and an improved survival rate have been reported. In this study, we analyzed the natural courses and survival statistics of SMA type I patients and compared the clinical characteristics... |
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- Case Report
- De novo interstitial direct duplication 8 (p21.3p23.1) with Pierre Robin sequence
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Soon Min Lee, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee, Jin Seong Lee, Kyung A Lee, Jong-Rak Choi
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Clin Exp Pediatr. 2009;52(5):603-606. Published online May 15, 2009
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The Pierre Robin sequence (PRS) is the nonrandom association of micrognathia, cleft palate, and glossoptosis, leading to respiratory and feeding difficulties that appear neurogenic rather than mechanical in causation. Genetic determinants are thought to underlie this functional and morphological entity, based on the existence of Mendelian syndromes with PRS. Here, we demonstrate the association of PRS with trisomy 8p due... |
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- Original Article
- Montelukast as an add-on therapy in bronchopulmonary dysplasia
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He Min Kim, Ji Eun Song, Soon Min Lee, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee
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Clin Exp Pediatr. 2009;52(2):181-186. Published online February 15, 2009
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Purpose : Inflammation plays a potential role in the pathogenesis of bronchopulmonary dysplasia (BPD). Strategies for preventing BPD include respiratory management, antioxidants, nutritional treatment, and others such as anti-inflammatory agents. We aimed to assess the safety, tolerability, and efficacy of montelukast (MK), a cysteinyl leukotriene 1 receptor antagonist, as an add-on therapy in BPD.
Methods : In addition to currently available... |
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- Clinical experience of therapeutic effect of peritoneal drainage on
intestinal perforation in preterm infants
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Jun Seok Lee, Kyo Yeon Koo, Soon Min Lee, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee, Seung Hoon Choi
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Clin Exp Pediatr. 2009;52(11):1216-1220. Published online November 15, 2009
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Purpose : To analyze and compare various cases in which peritoneal drainage was used as the primary treatment method in preterm infants with intestinal perforation.
Methods : Among the preterm infants of less than 28 weeks of gestation who were admitted to the neonatal intensive care unit (NICU) at the Gangnam Severance Hospital from April 2006 to April 2009, 7 who... |
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- Effect of surfactant lavage in severe meconium aspiration syndrome
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Soon Min Lee, He Min Kim, Ji Hyun Jeon, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee
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Clin Exp Pediatr. 2008;51(4):367-371. Published online April 15, 2008
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Purpose : The surfactant dysfunction may play an important role in meconium aspiration syndrome (MAS). We aim to evaluate the effect of surfactant lavage in the treatment of term infants with MAS.
Methods : The medical records of 15 neonates with severe MAS admitted at Yongdong Severance Hospital from 2005 to 2007 were reviewed and analyzed. Seven infants with severe... |
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- Oxygenation index as a respiratory parameter of respiratory distress
syndrome in preterm infants
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Ji Hyun Jeon, Ran Namgung, Min Soo Park, Kook In Park, Chul Lee
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Clin Exp Pediatr. 2008;51(2):145-149. Published online February 15, 2008
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Purpose : To examine whether changes of oxygenation index (OI) by postnatal age were different by the number of surfactant administration, and different between subgroups of survival and death.
Methods : From January 2005 to June 2006, preterm infants (n=84) diagnosed as respiratory distress syndrome (RDS) and treated with surfactant and ventilator were included. They were divided into two groups: Group... |
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- Case Report
- A Case of Fetal Alcohol Syndrome with Persistent Pulmonary Hypertension of the Newborn
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Jin-Ha Chang, Ran Namgung, Min-Soo Park, Kook In Park, Jin-Sung Lee, Chul Lee
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Clin Exp Pediatr. 2004;47(11):1220-1224. Published online November 15, 2004
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Fetal alcohol syndrome can be suspected in infants born to mothers with a prenatal history of alcohol abuse if the child exhibits characteristic facial features, together with intrauterine growth retardation, multiple neurological abnormalities, and multiorgan defects. If only a few of the above criteria are satisfied, the term fetal alcohol effects is used. We experienced a neonate who presented with... |
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- Original Article
- Clinical Trial of Domestically Developed Bovine Lung Surfactant YY-38 in Neonatal Respiratory Distress Syndrome
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Chul Lee, Jeong Nyun Kim, Min-Soo Park, Moon Sung Park, Shin Won Yoon, Wook Chang, Ran Namgung, Kook In Park, Dong-Gwan Han
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Clin Exp Pediatr. 1999;42(4):472-483. Published online April 15, 1999
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Purpose : We previously reported modified bovine lung surfactant YY-38(NewfactanⓇ) had a low surface tension, good hysteresis, and exhibited good pressure-volume curve in animal experiment (J Korean Pediatr Asso 1997;40:771-85). We performed multicenter clinical trial of NewfactanⓇ in neonatal RDS.
Methods : Seventy-seven infants with RDS(GA 31.8¡¾2.9 wks and BW 1,809¡¾592 gm) in 4 NICU were enrolled. After administration of... |
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- Physical and Biological Activity of Domestic Product of Modified Bovine Lung Surfactant
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Chul Lee, Min Soo Park, Moon Sung Park, Jung Nyeon Kim, Jong Wook Lee, Kwang Hyun You, Won Jae Kwag, Kook In Park, Ran Nam gung, Dong Gwan Han
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Clin Exp Pediatr. 1997;40(6):771-785. Published online June 15, 1997
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Purpose : Neonatal respiratory distress syndrome is caused by the deficiency of lung surfactant in
premature babies. For the treatment of RDS at present surfactants such as Surfacten․
(Tokyo-Tanabe Co., Japan) and Exosurf․ (Wellcome Co., USA) are used. As awarded the grant
from the Ministry of Science and Technology for a model research project of Medium-Technology
program, we have modified (supplemented) the bovine lung... |
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- Risk factors for Pulmonary Interstitial Emphysema(PIE) in Mechanically Ventilated Neonates with Hyaline Membrane Diseas
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Shin Won Yoon, Chul Lee, Jeong Nyun Kim, Ran Namgung, Dong Gwan Han, Myung Joon Kim
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Clin Exp Pediatr. 1997;40(3):318-326. Published online March 15, 1997
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Purpose : Pulmonary interstitial emphysema(PIE) is a common and serious complication
of mechanical ventilation in infants with hyaline membrane disease. This abnormal
collection of gases has two basic roentgenographic features; linear and cyst-like
radiolucencies. High positive inspiratory pressure was found to be the most significant parameter associated with development of fatal pulmonary interstitial emphysema. Without prompt conservative management such as lowering peak inspiratory... |
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- The Therapeutic Effects of Dexamethasone Therapy in Neonate with Bacterial Meningitis
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Eun Gyung Lee, Kook In Park, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Kwan Han
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Clin Exp Pediatr. 1995;38(5):602-611. Published online May 15, 1995
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Purpose : In experimental models of meningitis and in children with meningitis, dexametha-sone has been shown to reduce meningeal inflammation and to improve the outcome of disea-se. We studied the effects of dexamethasone administration in neonates(<2 month-old) with b-acterial meningitis.
Methods : We retrospectively reviewed the medical records of 30 neonates admitted to the nursery, the Yonsei University College of Medicine... |
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- Neonatal Neurosonographic Findings, Cerebral Doppler and Electrophysiological Findings in Infants with Motor Idsturbance
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Jae Kwang Kim, Kook In Park, Chang Il Park, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Kwan Han
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Clin Exp Pediatr. 1995;38(4):445-460. Published online April 15, 1995
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Purpose : Neurosonography, cerebral doppler and electrophysiological study are valuable in predicting neurodevelopmental outcome. The purpose of this study was to analyze characteristics of neonatal neurosonographic findigs, cerebral doppler and electrophysiological findings in infants withmotor disturbance.
Methods : The subjects were 33 infants hospitalized at Yonsei Severance Medical Center NICU from January, 1990 to December, 1992. 19 of these patients underwent... |
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- Case Report
- A Case of Hemimegalencephaly with Intraventricular Hemorrhage and Multifocal Intraparenchymal Hemorrage on Deep White Matter of Periventricular Area
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Jin Sung Ko, Kook In Park, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Gwang Han, Choon Sik Yoon
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Clin Exp Pediatr. 1995;38(4):561-566. Published online April 15, 1995
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Hemimegalencephaly is a rare congenital anomaly characterized by a intractable seizure an infantile death. This disease is a migrational disorder with enlargement of unilateral hemisphere, abnormal gyration of the cortex, the presence of large and atypical neuron, hetero trophic neuron at subcortical area and proliferation of astrocyte ect.
We observed a neonate with neonatal seizure, and the radiological evaluation revealed abnormal... |
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- A Case of Antley-Bixler Syndrome
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Young Rae Kim, Kook In Park, Choon Sik Yoon, Ran Namgung, Chul Lee, Dong Gwan Han
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Clin Exp Pediatr. 1995;38(4):582-585. Published online April 15, 1995
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Antley-Bixler syndrome is a very rare disese of characteristic feature of craniosynostosis, brachycephaly, midface hypoplasia, depressed nasal bridge, radiohumeral synostosis and bowing femur.
We presented a case of Antley-Bixtler syndrome with brief review of lituratures. |
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- Original Article
- Assessment of Infantile Mental and Motor Development Influenced by Breast Milk and Formula Feeding
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Chul Lee, Min Soo Park, Young Mi Chung, Hye Jung Joo, Kwang-Moon Kim, Dong Gwan Han
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Clin Exp Pediatr. 1995;38(3):289-296. Published online March 15, 1995
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Purpose : This study was undertaken to compare the mental and motor development, unsing Bayley Developmental Scale, during infancy(6-8 months of age) according to the choice of feeding, either breast milk of formula, as well as to evaluate its influence on physical growth.
Methods : The study population was 43 normal infants between 6 and 8 months of age, of birth... |
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- Clinical Studies of Metabolic Bone Disease of Prematurity
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Seung-Yeon Suh, Eun-Kyung Lee, Ran Namgung, Hae-Jung Joo, Min-Soo Park, Kook-In Park, Chul Lee, Dong-Gwan Han, Meung-Jun Kim, Jin-Suk Suh
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Clin Exp Pediatr. 1995;38(2):159-169. Published online February 15, 1995
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Purpose : Preterm formula used in Korea, theoretically does not supply the recommended mineral intake for optimal bone metabolism in very low birth weight infants(Formula 500-700 mg Ca/L, 300~370mg P/L, and 440IU of vitamin D/L). The purpose of this study is to identify th e possible etiologic factors and clinical course of rickets in these infants.
Methods : We recently identified... |
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- Effect of Glucocorticoid-Induced Hyperglycemia on Preventing Hypoxic-Ischemic Brain Damage by Dexamethasone in Neonatal Rat
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Kook In Park, Tae Seung Kim, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Gwan Han
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Clin Exp Pediatr. 1994;37(8):1035-1047. Published online August 15, 1994
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Purpose : We evaluated the protective effect of dexamethasone (DX) administration on brain damage produced in a perinatal model of cerebral hypoxia-ischemia in the rat. Since hyperglycemia has been shown to reduce hypoxic-ischemic brain injury (HI) in immature rat, we investigated the role of glucocorticoid-induced hyperglycemia in the neuroprotective mechanism of DX.
Methods : Hypoxic-ischemic brain injury in 7-day-old rats was... |
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- Case Report
- A Case of Phakomatosis Pigmentovascularis
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Seung Mo Park, Kook In Park, Hye Jung Joo, Ran Namgung, Chul Lee, Dong Gwan Han, Soo Il Chun
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Clin Exp Pediatr. 1994;37(8):1156-1161. Published online August 15, 1994
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In 1947, Ota et al. First reported a case of phakomatosis pigmentovascularis and defined a subgroup of this disease having a congenital generalized hemangioma and pigmented lesions including anmongolian spot-like lesion, nevus pigmentosus and nevus of Ota.
We experienced a case of phakomatosis pigmentovascularis type Iib in a 10-day old male baby, who since birth, had generalized nevus flammeus and... |
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- Original Article
- Intraventricular Hemorrhage in Full-Term Neonate
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Myoung Bae Jeon, Kook In Park, Choon Sik Yoon, Ran Namgung, Chul Lee, Dong Gwan Han
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Clin Exp Pediatr. 1994;37(6):776-785. Published online June 15, 1994
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Intraventricular hemorrhage is a common hemorrhagic cerebral disorder in premature, but occurs much less frequently in the full-term newborn. In order to obtain documentation of clinical and ultrasonographic characteristics of intraventricular hemorrhage in full-term, we performed cerebral ultrasonography on 602 newborn infants who had been admitted to neonatal intensive care unit at the Deppartment of Pediatrics, Yonsei University College of... |
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- Case Report
- A Case of Brain Damage in Surviving Monozygotic Twin After Intrauterine Death of Co-Twin
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Jae Young Choi, Kook In Park, Ran Namgung, Chul Lee, Dong Gwan Han, Tae Sub Chung
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Clin Exp Pediatr. 1994;37(5):701-706. Published online May 15, 1994
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Various anatomical defects have been described in the surviving twin who had a stillborn, macerated monozygotic co-twin Disseminated Intravascular Coargulation. The etiology is thought to be placental transfer of emboli or thromboplastic material through placental vascular anastomoses.
We experienced a case of monozygotic twin with deceased co-twin at 30 weeks of gestation and confirmed to have antenatal periventricular germinal matrix and... |
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- Original Article
- Tc-99m HMPAO Brain SPECT in a Patient with Neonatal Seizure and Right Cerebral Hemiatrophy
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Hye Young Kang, Kook In Park, Ran Namgung, Chul Lee, Chang Jun Coe, Dong Gwan Han, Tae Sub Chung, Woo Hee Jung
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Clin Exp Pediatr. 1994;37(3):397-404. Published online March 15, 1994
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Functional brain imaging is very important in the diagnosis and evaluation of the various neurologic disorders. In addition to electroencephalography (EEG) and positron emission tomography (PET), single photon emission computed tomography (SPECT) have increasingly gained importance in determination of disturbances in regional brain functions.
Both ictal and interictal Tc-99m hexamethyl-propyleneamine oxime single photon emission computed tomography (Tc-99m HMPAO SPECT) was done... |
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- Evaluation of Development of Normal Infants Using Bayley Developmental Test
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Young Mi Chung, Chul Lee, Kook In Park, Ran Namgung, Dong Gwan Han
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Clin Exp Pediatr. 1994;37(11):1508-1518. Published online November 15, 1994
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From April to September 1992, 40 infants with age 6 months to 8 months who had been born in Yongdong Severanve Hospital were studied for evaluation of their development using Bayley developmental test. The result obtained were as follow:
1) Mean mental developmental index(MDI) is higher than mean psychomotor developmental index (PDI) and the values are 101.9¡¾8.2 and 105.5¡¾9.8 respectively.
2) As... |
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- Risk Factors of Bronchopulmonary Dysplasia in Premature Infants Treated with Mechanical Ventilation and Restrictive Fluid Therapy
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Min Soo Park, Kook In Park, Hye Jung Choo, Moon Sung Park, Ran Namgung, Chul Lee, Dong Gwan Han
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Clin Exp Pediatr. 1994;37(10):1357-1363. Published online October 15, 1994
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In addition to many of the widely accepted risk factors of bronchopulmonary dysplasia(BPD), such as prematurity, oxygen toxicity, barotrauma, and infection, the amount of fluid intake during the early phase of life has recently been reported to be an important factor, especially the amount of colloid. Forty-one premature infants who were admitted to the NICU of Severance Hospital, Yonsei University... |
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- Clinical and Ultrasonographic Study on Prenatal Brain Damage in Newborn Infants
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Kook In Park, Dong Gwan Han, Ran Namgung, Chul Lee
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Clin Exp Pediatr. 1994;37(10):1364-1375. Published online October 15, 1994
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To determine the incidence of prenatal brain damage, and evaluate the clinical and neurosonographical characteristics, we prospectively examined 508 newborn infants with intracranial ultrasound within the first day of life who admitted to the NICU of Severance Hospital from June 1990 to January 1992 and reviewed maternal or neonatal medical records.
We found 12 cases(2.4%) of fetal brain... |
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- Case Report
- A Case of Cerebrocostomandibular Syndrome with Congenital Heart Disease
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Sang Heui Song, Kook In Park, Hye Jung Joo, Ran Namgung, Chul Lee, Dong Gwan Han
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Clin Exp Pediatr. 1993;36(4):574-578. Published online April 15, 1993
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Cerebrocostomandibular Syndrome is characterized by micrognathia, cleft palate, multiple thorax deformity and frequently, mental deficiency. Respiratory compromise is a common cause of death.
We experienced a case of cerebrocostomandibular syndrome with congeniyal heart disease in a 2 day old female baby with the chief complaint of cyanosis and respiratory difficulty since birth, She was delivered by cesarian section due to delayed... |
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- Original Article
- The Therapeutic Effects of Dexamethasone in Bronchopulmonary Dysplasia
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Min Joong Kwon, Kook In Park, Min Soo Park, Ran Namgung, Chul Lee, Dong Kwan Han
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Clin Exp Pediatr. 1993;36(12):1672-1680. Published online December 15, 1993
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We observed clinical features of 18 bronchopulmonary dysplasia (BPD) patients who were admitted to the neonatal intensive care unit in the Severance Hospital of Yonsei University College of Medicine from January 1. 1987 to June 30. 1991. Eight patients in whom ventilator settings were unchanged from for more than 5 days because of lack of improvement in pulmonary function. ... |
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- Case Report
- A Case of Transfusion-Associated Gragt-Verus-Host Disease in a Preterm Infant
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Hye Jung Joo, Seung Mo Park, Ran Namgung, Kook In Park, Jin Sung Lee, Chul Lee, Dong Kwan Han, Kir-Young Kim, Kwang-Hoon Lee, Kwang-Gil Lee
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Clin Exp Pediatr. 1993;36(11):1613-1620. Published online November 15, 1993
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Graft-versus-host disease is commonly observed after allogeneic bone marrow transplantation but rarely recognized transfusion or solid-organ transplantation. Transfusion-associated graft-versus-host disease can occur in immunosuppressed recipients and immunocompetent transplant recipients. The clinical manifestations of gastrointestinal or hepatic dysfunction, rash and pancytopenia should heighten the physician's index of suspicion for GVHD.
Among premature infants, only four cases have been reported to develop... |
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- Original Article
- Evaluation of the Development of High Risk Low Birth Weight Infants Using Bayley Developmental Test
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Chul Lee, Yil Seob Lee, Hyung Rae Cho, Dong Kwan Han
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Clin Exp Pediatr. 1993;36(1):38-48. Published online January 15, 1993
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Forty two high risk low birth weight infants who had been admitted in neonatal intensive care unit at Yongdong Severance Hospital from August 1987 to July 1990 and followed up in the high risk infants follow-up clinic were studied for evaluation of their development using the Bayley developmental test at the age of 9 month (corrected age).
The results obtained were... |
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- Statistical Observation for the Pediatric Patients in ICU
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Ki Hun Eum, Chang Ho Hong, Young Mo Sohn, Chul Lee, Pyung Kil Kim
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Clin Exp Pediatr. 1992;35(6):762-768. Published online June 15, 1992
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A statistical study was performed on 221 ICU cared pediatric patients who were admitted to the department of pediatrics, Yonsei university college of medicine, Seoul, Korea from Apr. 1983 to Mar. 1991.
The results were as follows :
1) Total number of subject were 221, it was 7.5% of total ICU patients and 1.3% fo total admitted pediatric patients. The male to... |
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- Erratum
- Measurement of Bone Mineral Density in Korean Newborns by Dual Photon Absorptiometry
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Kook In Park, Chul Lee, Ran Namgung, Duk Hi Kim, Dong Gwan Han
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Accepted January 1, 1970
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Bone mineral density (BMD), bone mineral content (BMC) and bone width (BW) of lumbar spine was measured in 37 term and 38 preterm appropriate-for-gestational-age (AGA) infants and 22 term small-for-gestational-age (SGA) infants who were delivered at Yonsei University Severance Hospital from January to September 1991 using dual photon absorptiometry (DPA). All of the infants were studied once within three days... |
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- Original Article
- Longitudinal Change of Cerebral Blood Flow Velocity in Neonates with the Doppler Technique
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Kook In Park, Dong Gwan Han, Ran Namgung, Chul Lee, Jin Suk Suh, Myung Joon Kim
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Clin Exp Pediatr. 1992;35(1):60-68. Published online January 15, 1992
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Eighty-one asymptomatic preterm, term-SGA, and full term infants who were delivered at Yonsei University Severance Hospital from January to July 1990 were studied with color duplex imaging doppler sonography to assess the postnatal changes of the cerebral blood flow velocity longitudinally. Pulsatility index (PI) and area under the velocity curve (AUVC) were calculated to quantitate changes in anterior
cerbral artery blood... |
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- A case of neonatal herpes simplex virus encephalitis.
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Kook In Park, Young Mo Sohn, Dong Soo Kim, Ran Namgung, Chul Lee, Dong Gwan Han, Won Young Lee, Ki Keun Oh, Myung Joon Kim
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Clin Exp Pediatr. 1991;34(9):1276-1285. Published online September 30, 1991
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Neonatal herpes simplex virus infection still remains a life-threatening infection for the newborn.
With an increasing incidence of genital herpes and an increase in the incidence of neonatal herpes
simplex virus infections, it is important that pediatricians and neonatologists continue to maintain a
high index of suspicion in infants whose symptoms may be compatible with herpes simplex virus
infections so that early identification leads... |
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- Predictive factors and initial selection of antibiotics in neonatal sepsis.
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Dong Chul Park, Chul Lee, Kook In Park, Ran Namgung, Dong Gwan Han
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Clin Exp Pediatr. 1991;34(6):755-762. Published online June 30, 1991
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For simplifying and standardizing the interpretation of usual findings for neonatal sepsis, prenatal
and perinatal factors, clinical symptoms and signs, method of management and hematologic findings
were evaluated as a screening test.
From the data obtained, a scoring system was formulated that assigns a score of 3 for diarrhea, 1.
5 for tachypnea, 1.5 for cyanosis, 1 for umbilical vessel catheterization, 1 for intravenous... |
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- The incidence of complications in severely obese children.
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Dong Hwan Lee, Chong Guk Lee, Chul Lee, Yong Seung Hwang, Sung Ho Cha, Yong Choi
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Clin Exp Pediatr. 1991;34(4):445-453. Published online April 30, 1991
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The measurement of body weight, height and blood pressure, urine sugar, oral glucose tolerance
test, S-GOT, S-GPT, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol tests were made
in 324 severely obese elementary, middle and high school students (218 boys and 106 girls) to know the
incidence of complication in these children. .
The results were as follow:
1) S-GOT or S-GPT were increased abnormally in 38.3% and fatty livers were... |
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- Effect of fluid restriction on postnatal weight and outcome in very low birth weight infants.
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Chul Lee, Hyeon Soo Lee, Ran Namgung, Dong Gwan Han
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Clin Exp Pediatr. 1991;34(3):348-354. Published online March 31, 1991
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We studied 45 very low birth weight infants for change in birth weight, urine output, serum Na
level, ventilatory support and outcome between two groups after fluid restriction therapy. Group 1
(n=17) were infants whose weight loss were more than 5% of birth weight. Group 2 (n=17) were
infants whose weight loss were more than 5% of birth weight.
1) Group 1 had more fluid... |
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- Transplacental transmission of hepatitis B virus from carrier nothers to neonates.
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Soh Yeon Kim, Chul Lee, Dong Gwan Han
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Clin Exp Pediatr. 1991;34(2):190-196. Published online February 28, 1991
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Neonates bom to hepatitis B carrier mothers at Yongdong Severance Hospital, Yonsei University
College of Medicine were sampled for hepatitis B viral markers using venous blood drawn from
external jugular vein within 3 hours after birth and the following results were obtained.
Two thousand nine hundred and seventy two pregnant women who received prenatal care at
Yongdong Severance Hospital, Yonsei University College of Medicine... |
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- A case of type VI Ehlers-Danlos syndrome.
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Ki Soo Pai, Young Mi Chung, Ran Namgung, Chul Lee, Dong Gwan Han
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Clin Exp Pediatr. 1991;34(12):1717-1723. Published online December 31, 1991
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Ehlers-Danlos syndrome is an inherited hetergenous disorder of connective tissue with characteris-
tic clinical manifestations. In this article, a case of Ehlers-Danlos syndrome is presented. A nine
months old female was admitted due to developmental delay. On physical examination, she had soft
velvety skin and corneal opacity. Both hip joints were positive for Barlow test. There was hyper-
mobility of both knee and elbow... |
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- Congenital cytomegalovirus infection: incidence and clinical outcome.
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Young Mo Sohn, Kook In Park, Chul Lee, Dong Kwan Han, Won Young Lee
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Clin Exp Pediatr. 1991;34(10):1365-1372. Published online October 31, 1991
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In order to assess the rate of congenital cytomegalovirus (CMV) infection in newborns, CMV IgG
antibody was studies at about 37.5 weeks gestation in 309 mothers and a positive rate of 96.4% was
obtained. Virus culture for CMV from urine of 514 neonates less than 1 week after birth resulted in
CMV growth in 6 neonates showing a 1.2% congenital infection rate. In... |
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- Dubowitz Neurologic Examination in Normal Neonates.
-
Young Soo Lee, Soh Yeon Kim, Dong Chul Park, Kook In Park, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1990;33(7):977-988. Published online July 31, 1990
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With the improvement in survival rate in high risk infants in the neonatal intensive care unit, there
is rising concern about the neurologic sequelae in these infants. In order to evaluate the neur-
ologic examination in normal neonates, 400 normal newborns were evaluated for a duration of
6 months from Mach 1989 to August 1989. Neonates greater than 37 weeks gestational age, birth
weight... |
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- Prolapse of Ileal Mucosa Through the Patent Omphalomesenteric Duct.
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Hwan Gyu Park, Ki Soo Pai, Jeong Wan Yoo, Kook In Park, Ran Namgung, Chul Lee, Dong Gwan Han, Eui Ho Hwang, In Joon Choi
-
Clin Exp Pediatr. 1990;33(12):1713-1717. Published online December 31, 1990
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The omphalomesenteric duct in the embryo is a communication between the yolk sac and primitive
gut. The duct closes by six to eight weeks of intrauterine life and disappears soon after. Patent
omphalomesenteric duct is a congenital anomaly which occurs when there is incomplete closure of the
duct during this period.
The authors experienced a cases whereby a 29-day old male baby had patent... |
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- Clinical Study of Umbilical Vessel Catheterization in Newborn Infants.
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Dae Shik Kim, Kook In Park, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1990;33(11):1503-1509. Published online November 30, 1990
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Umbilical vessel catheterization has become a common procedure in critically ill newborn infants.
We studied the usefulness and complications of indwelling umbilical vessel catheters in 164 patients
who were admitted to the neonatal intensive care unit of the Department of Pediatrics, Yonsei
University Hospital from January 1985 to December 1988.
The results were as follows:
1) Their birth weights ranged from 650 to 3,800 gm, and... |
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- The Effect of Phototherapy on Serum bilirubin Binding Capacity and Affinity in the Neonate.
-
In Suck Ryu, Chul Lee, Ran Namkung, Dong Gwan Han
-
Clin Exp Pediatr. 1990;33(10):1319-1325. Published online October 31, 1990
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Since the effect of phototherapy in the treatment of neonatal hyperbilirubinemia has been reported
30 years ago, phototherapy has been used widely for neonatal hyperbilirubinemia, but the exact
mechanism and the effect of light on the human body have not been fully determined.
Free bilirubin level in the serum is an important indicator for kemicterus, a complication of
neonatal hyperbilirubinemia. Free bilirubin level was... |
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- Exogenous Surfactant Replacement Therapy of Hyaline Membrane Disease: A controlled clinical trial.
-
Ran Namgung, Chul Lee, Kook In Park, Dong Gwan Han
-
Clin Exp Pediatr. 1990;33(1):22-34. Published online January 31, 1990
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We conducted a clinical controlled trial of exogenous surfactant replacement therapy in premature
infants with hyaline membrane disease at the neonatal intensive care unit of Yonsei University
Medical Center form Nov. 1987 to May 1988.
Sixteen premature infants with severe HMD were randomly assigned to control group or
surfactant-treated group. Eight infants (mean gestational age 29.9±2.8 week, mean birth weight 1,
425±308.9 gm) were given... |
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- A Study on Noninvasive Measurement of Blood Pressure in Normal Newborn.
-
Eun Hee Lee, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1989;32(9):1216-1223. Published online September 30, 1989
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Measurement of blood pressure in neonate is an important diagnostic procedure. But measurement
of blood pressure were not performed routinely because of difficulty in measuring blood pressure and
variable normal range according to measuring apparatus.
Recently some accurate and convinient apparatuses of measuring blood pressure have been
introduced in neonatal care, so normal blood pressure values of neonate are needed.
In this study, we establish... |
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- Unusual Forms of Pulmonary and Extrapulmonary Manifestations of Mycoplasmal Pneumonia.
-
Young Soo Lee, Chang Ho Hong, Chul Lee, Sung Gyu Lee
-
Clin Exp Pediatr. 1989;32(8):1064-1073. Published online August 31, 1989
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A clinical study was performed on 145 patients admitted to the Departement of Pediatrics, Yong
Dong Severance Hospital between July, 1984 and June, 1987 with the diagnosis of Mycoplasmal
pneumonia. This diagnosis was done when chest X-ray or auscultation of the chest showed signs of
pneumonia. Patients with cold agglutinin titrations of 1:64 or titrations with four fold increase during
follow up had Indirect... |
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- Ultrasonographic Diagnosis of Congenital Hypertrophic Pyloric Stenosis.
-
Shin Heh Kang, Chul Lee, Ran Namgung, Dong Gwan Han, Ki Keun Oh, Seung Hun Choi
-
Clin Exp Pediatr. 1989;32(6):756-764. Published online June 30, 1989
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|
The diagnosis of congenital hypertrophic pyloric stenosis has traditionally been made on the basis
of history and physical examination in the majority of patients. Imaging procedures such as UGI
series have been reserved for vomiting infats in whom the diagnosis was obscure. More recently
ultrasonography with the lack of hazards associated with radiation provides an additional method of
investigation which is accurate and diagnose... |
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-
- Two Cases of Poland Syndrome.
-
Kul Ha Yoo, Ki Soo Pai, Byung Ju Chung, Chul Lee, Dong Gwan Han, Jong Doo Lee
-
Clin Exp Pediatr. 1989;32(5):713-717. Published online May 31, 1989
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|
Poland syndrome is characterized by an absence of the pectoralis major muscle, with ipsilateral
defect of the upper extremity, usually syndactyly. The incidence of this syndrome has been estimated
at 1 per 25,000 to 77,000 persons and more than 100 patients have been described worldwide.
Recently, we experienced two patients, the one was 14 year old male, who showed absence of left
pectralis maior... |
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-
- Postnatal Weight Curve in Low Birth Weight(Appropriate for Gestational Age) Infants.
-
Kyoung Mi Park, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1989;32(5):606-619. Published online May 31, 1989
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|
Postnatal body weight changes were observed in 171 surviving infants with birth weights from 875
gm to 2,125 gm who were born at Severance Hospital, Yonsei University College of Medicine form
1981 to 1987.
Only infants whose sizes were appropriate for gestational age were included in the study. Infants
were divided into 5 groups by biπh weight, with the median weight were 2,000 gm,... |
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-
- A case of congenital posterior choanal atresia.
-
Dae Shik Kim, Ran Namgung, Chul Lee, Dong Gwan Han, Seung Kyu Chung
-
Clin Exp Pediatr. 1989;32(11):1546-1552. Published online November 30, 1989
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|
The congenital posterior choanal atresia is an uncommon, but not rare, disorder that may threaten
the newborn’s existence or give rise to chronic symptoms. As many as 50% of patients with choanal
atresia have other associated anomalies.
We experienced a case of congenital posterior choanal atresia without associated anomaly in 6 day
old female baby. The patient was hospitalized due to the main symptoms... |
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-
- 7 Cases of Group B Streptococcal Meningitis and Sepsis.
-
Young Wan Kim, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1988;31(7):873-880. Published online July 31, 1988
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|
We report 7 cases of Group B streptococcal meningitis and sepsis. Six of the patients were admitted
to the Department of Pediatrics, Severance Hospital and Youngdong Severance Hospital in 1986 and
one was admitted in 1979. The age of onset ranged from 10 to 34 days of age and all were cases of
late onset. The Clinical findings were fever, seizure, poor feeding,... |
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-
- A Study on the Blood Pressure Measurements in Newborn.
-
Ran Namgung, Ki Soo Pai, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1988;31(5):541-546. Published online May 31, 1988
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|
Non invasive blood pressures measured by the Dinamap monitor, an oscillometric device, were
compared with the invasive radial artery pressure in neonates.
There were 21 patients with a mean age of 16.5 days (ranges 7 days to 1 month) and a mean body
weight of 3.3 kg. The invasive radial artery pressures were recorded on a strip chart and comparisons
were made between the... |
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-
- Abdominal Ultrasonographic Findings in Patients with Kawasaki Disease.
-
Ho Taek Kim, Chang Ho Hong, Chul Lee, Sung Kyu Lee, Pyung Kil Kim, Ki Kun Oh
-
Clin Exp Pediatr. 1988;31(3):348-354. Published online March 31, 1988
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|
Kawasaki disease, first reported in Korea in 1973, is now one of the disease commonly encountered
in pediatric age group. It presents systemic symptoms including abdominal ones such as pain, nausea
and vomiting, etc. There have been several case reports of hydrops of the gallbladder occuring
concurrently with Kawasaki disease, and the abdominal symptoms of the disease are known to
correlate with hydrops of... |
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-
- A Case of Persistent Fetal Circulation.
-
Jong Kyun Lee, Chul Lee, Ran Namgung, Sung Kyu Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1988;31(2):234-240. Published online February 28, 1988
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|
The authors have experienced a case of persistent fetal circulation associated with hypocalcemia.
The baby was delivered with full-term by repeated cesarean section. He showed marked dyspnea 4
hours after birth and thereafter cyanosis appeared. So artificial ventilator had been applied combined
with tolazoline administration. The patient was treated successfully and discharged on 28th hospital
day without complications.
We present one case of persistent fetal... |
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-
- The Direct Coombs Test and Heat Elution Test in ABO Incompatible Hemolytic Disease of the Newborn.
-
Kook In PArk, Chul Lee, Ran Namgung, Dong Gwan Han, Kir Young Kim
-
Clin Exp Pediatr. 1988;31(12):1633-1640. Published online December 31, 1988
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|
The clinical study on 28 cases of ABO HDN who were diagnosed at Pediatric Department of
Severance hospital and Yong Dong Severance hospital, Yonsei University for last 5 months was. And
in these cases, heat elution test in combined with direct Coombs test using standard techniques were
performed to evaluate the clinical significance of serological diagnosis.
The following results were obtained.
1) Of 28 ABO HDN... |
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-
- Neurosonographic Follow-up Study in Low Weight Infants.
-
Yil Sub Lee, Chul Lee, Ran Namgung, Dong Gwan Han, Ki Keun Oh
-
Clin Exp Pediatr. 1988;31(12):1573-1579. Published online December 31, 1988
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|
Serial neurosonographic examinations were performed in 34 low birth weight infants who were
admitted to the neonatal intensive care unit of Yong-Dong Severance Hospital. Among them, 14 (41
%)were found to have periventicular-intraventricular hemorrhage. The initial hemorrhage occured in
the first three days of life among 71% infants. After initial hemorrhage, hemorrhage was decreased
in size and thereafter absorbed. Fourteen (44%) infants demonsrated cysts... |
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-
- A Study of Transcutaneous Oxygen Monitoring in Neonatal Intensive Care.
-
In Suck Ryu, Chul Lee, Ran Namkung, Dong Gwan Han
-
Clin Exp Pediatr. 1988;31(11):1417-1424. Published online November 30, 1988
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|
191 simultaneous measurement of arterial PO2 and transcutaneous PO2 were made in 14 sick infants
from November, 1986 to April, 1987 who were admitted to the Neonatal Intensive Care Unit of
Yongdong Severance hospital.
Differences between TcPO2 and PaO2 in these sick infants were evaluated in the relation to systolic
blood pressure, hematocrit, arterial pH and birth weight. There was a linear relationship and... |
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-
- Bilirubin-Binding Capacity of Albumin in Korean Neonates.
-
Jung Bae Lee, Chul Lee, Ran Namgung, Dong Gwan Han, Kyung Son Song
-
Clin Exp Pediatr. 1988;31(10):1259-1266. Published online October 31, 1988
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|
The binding of bilirubin by albumin is thought to play an important role in the pathogenesis of
kemictems. Free bilirubin hypothesis has led to develop methods to evaluate the binding capacity and
affinity of bilirubin to albumin in the plasma. Horseradish peroxidase oxidation of free bilirubin can
estimate the level of free bilirubin, bilirubin binding capacity and bilirubin binding affinity.
Twenty four term infants... |
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-
- The Result of Intensive Care on the very Low Birth Weight Infants(1001~1500gm).
-
Seo Jeong Kim, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1988;31(1):29-39. Published online January 31, 1988
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|
The clinical study on the results of intensive care was performed on the 137 very low birth weight
infants with birth weight of 1001-1500 gram who were admitted to the neonatal intensive care unit
of Severance hospital from 1981 to 1986.
The results were as follows.
1) The range of gestational age of very low birth weight infants was from 22 to 40 weeks, most
predominantly... |
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-
- Case Report
- Neonatal Tetanus Treated with Intermittent Positive-Pressure Ventilation.
-
Ran Namgung, Chuhl Joo Lyu, Chul Lee, Youn Ha Kang, Dong Gwan Han
-
Clin Exp Pediatr. 1987;30(6):671-676. Published online June 30, 1987
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|
We report our experience with Neonatal Tetanus treated with Intermittent Positive-Pressure
Ventilation combined with Neuromuscular blockade and high dose diazepam.
Duration of mechanical ventilation was ranged from 15 days in case 1 to 36 days in case 2.
Pneumonia with atelectasis and sepsis due to pseudomonas cepacia was complicated in case 2, but
cleared up with sensitive antibiotics and vigorous physiotherapy.
Muscle relaxation and sedation... |
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-
- Original Article
- The Effect of Hepatitis B Vaccination on Newborns of Hepatitis B Carrier Mothers.
-
Ho Taek Kom, Pyung Kil Kim, Chang Ho Hong, Chul Lee
-
Clin Exp Pediatr. 1987;30(11):1228-1235. Published online November 30, 1987
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|
The transmission of hepatitis B virus (HBV) from carrier mothers to their infants is a serious
problem in many countries and the transmission rate is reported to be as high as 60%.
The best preventive method of perinatal transmission is hepatitis B immune globulin (HBIG) which
confers a passive immunity and HB vaccine which confers an active immunity. However, the exact
dosage and the... |
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-
- Chronic Hepatitis B in Children.
-
Don Gyu Yang, Jong Kyun Lee, Pyung Kil Kim, Chang Ho Hong, Chul Lee
-
Clin Exp Pediatr. 1987;30(10):1115-1123. Published online October 31, 1987
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|
We reviewed 19 cases of chronic hepatitis B confirmed by liver biopsy during the 3 years and 5months from March 1983 to July 1986 at Young Dong Severance Hospital.
The following results were obtained:
1) There were 16 boys and 3 girls with ages ranging from 7 months to 14 years old (mean+S.D.; 6.5 ±0.9 years).
2) There were 2 cases (10.5%) of chronic persistent... |
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-
- Case Report
- A Case of Leiner's Disease Kee Hyuck.
-
K H Kim, Ran Nam Gung, Chul Lee, Dong Kwan Han, Yoon Kee Park
-
Clin Exp Pediatr. 1986;29(8):902-906. Published online August 31, 1986
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We have experienced a case of Leiner’s disease characterized by generalized seborrheic dermatitis,
intractable, severe diarrhea, marked wasting, and recurrent local and systemic infections.
We are reporting this case with brief review of literatures.
|
-
-
- Case Report
- Cranial Ultrasonographic Diagnosis for A Case of intracranial Hemorrhage in Early Infancy due to Vitamin K Deficiency.
-
Chul Lee, Ki Keun Oh
-
Clin Exp Pediatr. 1986;29(12):1377-1381. Published online December 31, 1986
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|
Since the initiation of routine vitamin K prophylaxis in the newborn, the incidence of
hemorrhagic disease of the newborn has been dramatically decreased. We report here a
case of intracranial hemorrhage due to vitamin K deficiency in a 2-month-old which was
diagnosed with cranial ultrasonography. With advent of cranial ultrasonography which is
portable, relatively inexpensive and noninvasive, the intracranial hemorrhage is easily
confirmed especially as... |
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-
- Original Article
- Clinical observation in the Clavicle Fracture in Newborn.
-
Kee Hyuck Kim, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1986;29(12):1319-1323. Published online December 31, 1986
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The following is the result of a retrospective clinical study on the clavicle fractures iit 33 newborns who were delivered at Yonsei University Medical Center during the eight years between 1978 and 1985.
1) The incidence of clavicle fractures was 2 per 1,000 deliveries and there was no difference in incidence by sex.
2) The incidence of clavicle fracture by the birth weight was... |
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-
- Clinical observation in 72 Cases with Neonatal Sepsis.
-
Jae Seung Yang, Ran Namgung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1986;29(12):1309-1313. Published online December 31, 1986
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|
Since the clinical features of neonatal sepsis were first reported by Dunham in 1933,
there have been many studies. But because of the uncertain early symptoms and it’s rapid
progression, the mortality rate of neonatal sepsis runs still high. We are reporting 72 cases of neonatal sepsis confirmed by clinical symptoms and blood culture studies over 3 years and 5 months between... |
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-
- Clinical Studies on Enteropathogenic E.Coli Enteritis in a Newborn Nursery.
-
Chang Hyun Yang, Ran Nam Gung, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1986;29(11):1187-1195. Published online November 30, 1986
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We experienced 20 cases of infantile diarrhea caused by Enteropathogenic E. Coli during 2 months from May. 1985 to Jun. 1985 at Yonsei medical center, Newborn nursery. The onset of illness is ususally slow vague signs of reluctance to feed lethargy, spitting up of formula, mild abdominal distention and diarrhea. The outbreak abated abruptly after institution of strict aseptic technique,... |
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-
- Incidence and Risk Factors of Periventricular and Intraventricular Hemorrhage in Low Birth Weight Infants.
-
Chul Lee, Heung Dong Kim, Ki Keun Oh, Dong Gwan Han
-
Clin Exp Pediatr. 1986;29(11):1179-1186. Published online November 30, 1986
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|
Real time ultrasound scans were performed on 54 low-birth weight infants within the 7th 'birth day.
Fifty infants were inborn. The incidence of periventricular and intraventricular hemorrhage (PV-IVH)
was 38.9%. Seven of 21 infants had mild hemorrhage (Papile, grade I and II): Others sustained severe hemorrhage(Papile, grade III and IV ). Low Apgar score, respirator care and use of dopamine... |
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-
- A Clinical Study of Wet Lung Disease.
-
Soon Wook Lim, Jae Seung Yang, Chul Lee, Dong Gwan Han, Chin Suck Suh
-
Clin Exp Pediatr. 1985;28(9):852-860. Published online September 30, 1985
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|
The authors studied 36 cases of wet lung disease who were born and admitted to pediatric department of Severance hospital from January 1981 to June 1984. following results were obtained: 1)The incidence of wet lung disease was 0.5% and the predisposing factors were male sex(78%), full term(75%), C-section(58%) and multipara(72%). 2)Number of cases whose Apgar score were above 7 werp... |
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-
- Case Report
- A Case of Thyroid Papillary Adenocarcinoma.
-
Duk Hi Kim, Chul Lee, Pyung Kil Kim, Byung Soo Kim, Yi Ho Hwang, Kyung Sik Lee, Woo Hee Chung
-
Clin Exp Pediatr. 1984;27(3):288-292. Published online March 31, 1984
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We report a case of thyroid papillary adenocarcinoma in a 5 year 1 month old boy. His major problem was palpable thyroid nodule & cervical lymph nodes. Extensive bilateral pulmonary metastasis was noticed. The metastatic thyroid carcinoma was regressed after therapeutic doses of radioiodine without total thyroidectomy.
|
-
-
- Original Article
- Clinical Study of the role of Exchange Transfusion for Treatment in Neonatal DIC.
-
Myung Shik Lee, Jin Sung Lee, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1984;27(12):1151-1161. Published online December 31, 1984
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|
This study was made of 9 cases of neonatal septicemia complicated with DIC and sclerema,
who were admitted to the pediatric department of YUMC from January 1981 to June 1983.
The following results were obtained;
1) A higher incidence was observed in males(77.8%), low birth weight(66.7%) and1 pretnature(77.8%).
2) The mean onset of sepsis was noticsd on 4.4 days of life. The most common presenting symptoms... |
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-
- A Clinical Observation of Congenital Anomalies Born with Hydramnios.
-
Kook In Park, Myung Shik Lee, Chul Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1984;27(10):991-999. Published online October 31, 1984
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|
This is a clinical observation of congenital anomalies in 55 newborn infants associated with hydramnios.
These infants were born at Severance Hospital from Sep. 1975 to Jun. 1983. The results were as follows: 1) The frequency of hydramnios was 49 cases in 160,060 deliveries in that period, which was 0.31%. 27 infants (49.1%) had congenital anomalies of 55 infants associated with hydramnios... |
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-
- A Clinical Observation of Meconium Aspiration Syndrome.
-
Chul Lee, Kook In Park, Jean Young Lee, Dong Gwan Han
-
Clin Exp Pediatr. 1984;27(10):958-964. Published online October 31, 1984
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The Authors observed 51 cases of meconium aspiration syndrome in newborns who were born at Severance Hospital during the period of Jan. 1980 through Jun. 1983. The following results were obtained: 1) The incidencs of meconium aspiration syndrome was 0.6%(51 cases). 2)88.2% of newborn with meconium aspiration syndrome was weighing more than 2,500 gm and 93.1% of that was with a... |
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-
- Case Report
- Two Cases of Di Guglielmo Syndrome.
-
Seok Ku Kim, Seong Ja Jeon, Chul Lee, Myung Ho Lee, Sook Ja Park
-
Clin Exp Pediatr. 1983;26(3):289-284. Published online March 31, 1983
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|
Di Guglielmo Syndrome is a relatively rare disease in childhood and refers to an acute or
chronic myeloproliferative disorder in which erythrocytes and their precursors are the cells
predominantly involved in the leukemic process. We experienced two cases of Di Guglielmo syndrome,
an llyear-old girl and a 14 year-old boy, who had the chief complaints of severe anemia, fever,
dizziness and general... |
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-
- A case of myelofibrosis.
-
Hae Jung Cho, Keun Chull Choi, Chul Lee, Myong Ho Lee, Sook Ja Park
-
Clin Exp Pediatr. 1982;25(9):945-953. Published online September 30, 1982
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|
The so called “Myelofibrosis” within the category of myeloproliferative disorders consists
of various degrees of leukoerythroblatosis, bone marrow fibrosis, and extramedullary hema-
topoiesis with hepatosplenomegaly.
Primary myelofibrosis occurs predominantly in adults and few in childhood. We experie-
nced one case of myelofibrosis, at 17 month old male patient.
He was admitted due to intermittent fever, pallor and abdominal distension. On admission,
hepatosplenomegaly, anemia and generalized petechia... |
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-
- Original Article
- Study on cord blood hemoglobin and etiology of neonatal anemia.
-
Chul Lee, Hae Jung Cho, Myung Ho Lee, Sook Ja Park, Young Hae Lee
-
Clin Exp Pediatr. 1982;25(9):906-913. Published online September 30, 1982
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|
Capillary samples obtained by skin prick, generally from the heel or toe, have a higher
hemoglobin Concentration than simultaneously collected venous samples. So, capillary values
should not be compared to previously obtained cord venous blood values when one is looking
for changes in hemoglobin, concentration during the first week of life. Cord venous blood
hemoglobin and hemotocrit of 309 normal newborn infants have been... |
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-
- Clinical Study of Juvenile Diabetes Mellitus.
-
Keun chull Choi, Seok ku Kim, Chul Lee, Myung ho Lee
-
Clin Exp Pediatr. 1982;25(5):489-497. Published online May 31, 1982
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We have observed 9 cases of juvenile diabetes mellitus who were admitted to Pediatrics Department of Presbyterian Medical Center in Jeon-ju, during period of 7 years and 2 months from Jan, 1974 to Mar, 1981. The following results were obtained. 1) Incidence of juvenile diabetes mellitus was 0.088% of all patients who were admitted to Pediatric Department ward during period... |
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-
- Case Report
- A Case of Salmonella Meningitis.
-
Oh Kyung Lee, Seok Ku Kim, Chul Lee, Myung Ho Lee
-
Clin Exp Pediatr. 1982;25(12):1270-1274. Published online December 31, 1982
-
|
|
Salmonella meningitis is characterized by rapid clinical course and poor prognosis in young
children.
Authors experienced a case of Salmonella meningitis in 16-month-old boy child, who was
admitted to the pediatric department with high fever and diarrhea for 5 days.
The diagnosis was confirmed by positive culture of Salmonella typhi on CSF and Blood.
In this article, we emphasize the atypical symptoms and sign of... |
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-
- A Case of Rt. Renal Agenesis Combined with Cryptorchism and Neuroblastoma.
-
Hee Jung Chung, Chul Lee, Pyung Kill Kim, Chang Jin Kim, Kwang Kill Lee, Yu Bok Lee, Ki Keun Oh
-
Clin Exp Pediatr. 1981;24(7):677-684. Published online July 15, 1981
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|
Congenital unilateral renal agenesis is a rare congenital anomaly. Furthermore, renal agenesis associated with neuroblastoma and cryptorchism is more rare in incidence. Recently we experieced a case of Rt. renal agenesis combined with cryptorchism and neuroblastoma. We diagnosed it with IVP and selective renal angiography and confirmed it with explolaparotomy and biopsy. We reviewed the literatures on renal agenesis, cryptorchism... |
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-
- Original Article
- Diagnostic Value of Serum Immunoglobulins in Glomerulonephritis.
-
Pyung Kil Kim, Kyo Sun Kim, Chul Lee, Nan Ae Kim, Jae Seung Lee
-
Clin Exp Pediatr. 1981;24(7):652-658. Published online July 15, 1981
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|
Serum immunoglobulin concenatrations were measured in 156 patients with various types of glomerulonephritis such as acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. 1) Serum IgG level was above normal mean in acute poststreptococcal glomerulonephritis, and normal range in Henoch-Scholein purpura nephritis. Serum IgG concentrations were significantly reduced in minimal lesion nephrotic syndrome. 2) Serum IgA concentrations... |
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-
- Selective Protein Index and Response to Treatment in the Childhood Nephrotic Syndrome.
-
Chang Ho Hong, Chul Lee, Pyung Kill Kim, Duk Jin Yun
-
Clin Exp Pediatr. 1981;24(7):645-651. Published online July 15, 1981
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|
In a group of 59 children with nephrotic syndrome who had been admitted to Severance Ho-spital, during the period of 2 years from July of 1978 till June of 1980, the histological picture seen on renal biopsy, the selective protein index, and the response to the steroid therapy were studied. The degree of selective protein index is not related to... |
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-
- Case Report
- Two Cases of Cri Du Chat(5p-) Syndrome.
-
Han Soo Choi, Sung Seek Lee, Chul Lee, Kwan Sub Chung, Pyung Kil Kim, Kir Young Kim, Sa Suk Han
-
Clin Exp Pediatr. 1981;24(6):597-602. Published online June 15, 1981
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|
We have experienced two cases of the Cri Du Chat Syndrome. The first case, 1 and 11/12 year old female, was admitted to evaluated profound mental retardation and failure to thrive. The other, 3 month old female, visit this dept for cat-like cry. They had the typical clinical characteristics of the Cri Du Chat Syndrome and showed showed the classical... |
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-
- A Case of Yersenia Enterocolitica Enteritis Simulating Shigellosis.
-
Hong Jin Kim, Hee Chung Chung, Chul Lee, Pyung Kil Kim, Yun Sub Chung
-
Clin Exp Pediatr. 1981;24(5):492-496. Published online May 15, 1981
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We report a case of gastroenteritis due to Yersinia enterocolitica in a 7month old male infant who was misdiagnosed as shigellosis at onset of illness. He was treated with Gentamicin successfully. A marked improvement was resulted in clinical symptoms and laboratory finding at the time of discharge. It is a second case of Y.enterocolitica which is proved by stool culture... |
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- Original Article
- A Case of Congenital Hypoplastic Anemia.
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Dong Soo Kim, Chul Lee, Hong Kyu Lee, Kir Young Kim, Duk Jin Yun
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Clin Exp Pediatr. 1980;23(9):771-775. Published online September 15, 1980
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Authours have observed a case of congenital hypoplastic anemia in 21 months old Korean male patient who was diagnosed through aspirations of bone marrow. His hematologic improvement was followed by administrations of prednisolone. A brief review of related literature was made. |
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- Case Report
- A case of Scurvy.
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Jun Hee Sul, Chul Lee, Duk Hee Kim, Pyung Kil Kim, Duk Jin Yun, Ki Keun Oh
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Clin Exp Pediatr. 1980;23(9):730-736. Published online September 15, 1980
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Scurvy is a manifestation of deficiency of vitamin C, which was characterized by follicular hyperkeratosis, hemorrhagic manifestation, fatigue, muscular ache and pains, swollen jonts, swollen bleeding gums, and peripheral edema. Rescently we experienced a cases of scurvy in 13 month old boy who had been nourished by artificial feedings with ricegruel without additional vitamin C. Rentgenographic findings of bone revealed... |
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- Renal Changes in Henoch-Schonlein Purpura with Normal Renal Function.
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Chul Lee, Pyung Kil Kim, Duk Jin Yun, In Joon Choi
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Clin Exp Pediatr. 1980;23(9):717-723. Published online September 15, 1980
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Henoch-Schonlenin purpura is one of the most common cause of purpura of children in Korea at present time, but well summarized report about the incidence in Korea is not submitted yet. Renal involvemnet in Henoch-Schonlein purpura nephritis is one of the important cause of end stage kidney disease in chidhood, accounting for about 15% of children who are on dialysis... |
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- The First Case of Renal Transplatation in Childhood in Korea.
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Pyung Ki Kim, Chul Lee, Jae Seung Lee, Duk Jin Yun, Ki ll Park, Tae Jung Kwon, In Joon Choi
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Clin Exp Pediatr. 1980;23(8):674-681. Published online August 15, 1980
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We successfully transplanted kidney of mother to 13 year old boy who had been suffered from chronic renal failure for 11 months. This is the first case of renal transplantation in childhood in Korea. Patient was treated chronic renal failure with peritoneal dialysis, hemodalysis and transfusion duing 1 month before transplantation. Both kidneys revealed grade 4 vesico-ureteral renal tissue by... |
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- Original Article
- Computerized Transverse Axial Tomography in Seizure Disorders.
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Dong Soo Kim, Chul Lee, Chang Jun Coe, Duk Jin Yun, Jung Ho Suh
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Clin Exp Pediatr. 1980;23(8):646-652. Published online August 15, 1980
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Seizure is the frequent disorder in childhood and detection of organic lesions is very important for both the determination of a therapeutic plan and the prognosis of the patient. Computerized transverse axial tomographic examination of 106 patients with seizure in Severance Hospital, Yonsei University from Dec. '77 to Dec. '79 was reviewed and analysed the following results were obtained. 1.... |
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- Serum C3 Levels in Acute Poststerptococcal Glomerulonephritis.
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Jun Hee Sul, Chul Lee, Pyung Kil Kim, Duk Jin Yun
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Clin Exp Pediatr. 1980;23(6):474-478. Published online June 15, 1980
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Acute Poststreptococcal glomerulonephritis is generally stated to be the most common cause of acute nephritis in childhood. The activity of serum complement has been studied in various diseases in an attempt to accumulate evidence of antigen-antibody reaction. In acute poststreptococcal glomerulonephritis, several investigators have reported a decrease in serum complement early in the course of disease. This paper reports on... |
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- Case Report
- A cases of Congenital Nephrogenic Diabetes Insipidus with Bilateral Hydronprosis.
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Young Mo Sohn, Chul Lee, Pyung Kil Kim, Duk Jin Yun
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Clin Exp Pediatr. 1980;23(5):417-422. Published online May 15, 1980
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A 13 year old boy was diagnosed as primary nephrotic diabetesinsipidus, whose symptom has been devloped from 3 years of age, subsequetly he developed bilateral hydronephrosis and neurogenic bladder. His pedigree could be explored 5 generations and represented inheritace as X-linked recesslive transmission, He was treated with indomethacin 2mg/Kg/day plus chlorothiazid 500mg/dau and this new method shows markedly decreased urine... |
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- Original Article
- The Study of Fetomaternal Transfusion in Korea.
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Chul Lee, Jun Hee Sul, Kir Young Kim, Duk Jin Yun
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Clin Exp Pediatr. 1980;23(12):983-990. Published online December 31, 1980
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Blood samples from mothers during labor and after delivery were tested for the occurrence of fetomaternal transfusing using Nierhaus acid elution technique. Fetomaternal transfusion had occured 1/2 of the mothers after delivery, 2/3 of the mothers during labor. The fetomateonal transfusions after delivery were most often less than 4.0?? and only few percent had fetomaternal transfusions more than 4.0??. Complicated... |
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- Therapeutic Effect of Rifampin in Shigellosis.
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Chul Lee, Jun Hee Sul, Pyung Kil Kim, Duk Jin Yun
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Clin Exp Pediatr. 1980;23(10):791-797. Published online October 15, 1980
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Twenty one infants and children were entered into the study protocol when bacteriologic diagnosis of shigellosis was made by stool culture indenification. Fifteen patients were treated at Inje Hospital in Kangwon Do and six patients were treated at Severance Hospital in Seoul. Susceptibility studies were revealed that ampicillin was resistant in all cases. Gentamicin and Panimycin which are aminoglycosides were... |
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- Fetomaternal Transfusion.
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Dong Gwan Han, Chul Lee, Kir Young Kim, Hyo Kyu Kim
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Clin Exp Pediatr. 1979;22(4):306-312. Published online April 15, 1979
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From Feb, 1977, through Aug. 1977, 100 venous blood samples obtained from women within 48 hr after delivery were examnied for fetomaternal transfusion by the Nierhaus acid elution technique. Blood smears were scanned at 100 high power field for enumeration of fetal erythrocytes. 1. The incidence of fetomaternal transfusion was 26% 2. The incidence of fetomaternal transfusion was the highest... |
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- Comparative Study
- Acute Poisoining of Infants and Children-Comparative Study of last 2 Decades in Urban and Rural areas.
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Chul Lee, Soo Hyung Kim, Eoh Jung Lee, Ki Young Lee, Pil Rae Chung, Jong Soo Kim
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Clin Exp Pediatr. 1978;21(7):515-525. Published online July 31, 1978
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Two hundred and thirteen cases of acute poisoning who were admitted in pediatric wards of Severance Hospital and Won ju Christian Hospital from April, 1966 to March, 1976 (10 years) were statistically analyzed and compared it with the statistical study of same hospitals from April, 1956 to March, 1966 (10 years). 1. Incidence of poisoning was 1.2% of all admitted... |
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- Case Report
- Five cases of Congenital Hydronephrosis in Infancy.
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Chul Lee, Hong Kyu Lee, Jae Song Kim, Dong Gwan Han, Duk Jin Yun, Jin Moo Lee
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Clin Exp Pediatr. 1978;21(5):396-402. Published online May 31, 1978
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This is a clinical observation of five infants associated with congenital hydronephrosis experienced at the Pediatric Department of Severance Hospital. The results were as follows: 1. The age distribution was from one day to seven months with the sex radio of 4 : 1 with male predominance. 2. The signs most freguently found were palpable abdominal mass and abdominal distension.... |
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